With us, tissue is not an issue
Human heart, skeletal muscle and kidney models, measured automatically on the DiNAQUBE™.
See how it works
We are a clinical research organization and develop life science tools
To help you research more effortlessly with 3D human tissue technology
The EHT¹ workflow
EHTs, created from human induced pluripotent stem cells, are 3D cardiac constructs that accelerate preclinical research and enhance personalized medicine studies.
Manual tissue analysis is a thing of the past. That’s a promise.
01Engineer Human Tissue
01Engineer Human Tissue
Heart (EHT), skeletal muscle (EMT) and kidney organoids from control, patient-derived or gene-edited hiPSC lines.
Engineered Heart Tissues (EHTs) are three-dimensional, fibrin-based cardiac constructs derived from human induced pluripotent stem cells (hiPSCs). Our innovative technology combines hiPSCs with 3D tissue engineering to simulate human heart tissues, enabling precise cardiac safety and efficacy testing, disease modeling and precision medicine including gene therapy applications.
EHTs not only facilitate the rapid translation of research findings into preclinics but also provide a powerful testbed for personalized medicine approaches.
02Run sterile tests in 90 seconds
02Run sterile tests in 90 seconds
With the DiNAQUBE™, our AI-driven measurement platform, research has never been more effortless. In just 90 seconds, you can run sterile, video-optical measurements that allow for long-term, non-invasive studies.
The DiNAQUBE™ enables the simultaneous analysis of up to 24 Engineered Heart Tissues (EHTs) per run, combining contractility measurements, electrical pacing, and fluorescence-based readouts such as calcium transients. This comprehensive approach allows you to capture essential time-dependent effects, while our automated tissue recognition technology ensures accurate, reproducible, and user-independent results.
03Interpret ready-to-use data
03Interpret ready-to-use data
With DiNALYTIQS™, our web-based data analytics solution. Designed for ease of access and use, you can effectively retrieve and analyze human tissue data measured with our DiNAQUBE™. Features such as customizable reporting, automated quality control through AI, and integration with multiple data sources allow you to focus more on data interpretation and less on data management.
In addition, AI capabilities simplify and accelerate the classification and comparison of measurements, providing valuable insights and ensuring consistency in data quality and analysis.
Integrates omics and stores GLP-compliant data on-prem or in DiNACLOUD™.
SPOTLIGHT · HFpEF
Human HFpEF in a dish. Diastolic dysfunction you can measure.
About us
Trust those with a legacy in leading edge technology
Started with the heart. Now heart, muscle and kidney.”
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from our lab
Services for early-stage drug development
in your lab
The DiNAQUBE™
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EHTs, created from human induced pluripotent stem cells, are 3D cardiac constructs that accelerate preclinical research and enhance personalized medicine studies.